Older women with fibrous clitoris












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The vagina is a fibromuscular tube that connects the uterus with the vestibule of the external genitalia. There is a deeper surrounding fibrous layer above the muscularis which provides structural support to the vagina, and is rich is collagen and elastin, to allow for expansion of the vagina during sexual stimulation. They only become obvious if they reach painful, spasmotic levels dysmenorrheic pain. In a number of women this area swelled up to the size of a kidney bean and projected into the vaginal lumen.

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Clitoris Metastasis From A Retroperitoneal Leiomyosarcoma

Autonomic efferent innervation to the upper two thirds of the vagina is through the utervaginal plexus, which contains both sympathetic and parasympathetic fibers. The enhanced blood flow is activated by the VIPergic innervation of the large vessels supplying the epithelium and the transudation possibly aided by the CGRP calcitonin gene regulating peptide enhanced permeability of the capillary tufts. The corpora cavernosa of the clitoris measures up to 5 inches in length. Breakdown of the glycogen by bacteria in the vagina produces lactic acid, causing the vaginal environment to hae an acid pH of about 3. The clitoris consists of a midline shaft lying in the medial sagittal plane about cm long and cm wide which bifurcates internally into paired curved crura cm long attached to the under surface of the pubic symphisis. On stimulation this space becomes vasocongested and creates an erotic pleasurable response. For detumescence, the arterial polsters contracted while those in the veins and a-v anastomoses relaxed, reducing the flow to the lacunae and allowing the blood restricted in them to flow away.

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Nerves from the uterovaginal plexus travel within the uterosacral and cardinal ligaments, to supply the proximal two-thirds of the vagina. The erectile tissue of the clitoral shaft consists of two parallel corpora cavernosa surrounded by a fibrous sheath tunica albuginea. The corpora cavernosa of the clitoris measures up to 5 inches in length. The internal mucosal layer. The lamina propria has many thin-walled blood vessels that contribute to diffusion of vaginal fluid across the epithelium. The glans is covered by a clitoral hood formed in part by the fusion of the upper part of the two labia minora. This epithelium undergoes hormone-related cyclical changes including slight keratinization of the superficial cells during the menstrual cycle.

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Description: Nevertheless, human clitoral erectile tissue has the capacity to develop drug-induced priapism which responds by detumescing following administration of a-adrenergic agonists. Synthesis of cyclic nucleotides was also carried out in intact cells in culture in response to sodium nitroprusside NO donor and forskolin direct adenylate cyclase activator. It acts in transport of sperm to the uterus and in expulsion of the newborn. Glycogen, stored in the epithelial cells, reaches maximal levels at ovulation after which time the glycogen-rich superficial layer of epithelium is shed. During arousal to orgasm, there is an increasing vaginal luminal pressure. The results of this study supports a role for nitric oxide in regulation of human clitoral corpus cavernosum smooth muscle tone. They can last for seconds. This erotic sensitive area is located in closer relation to the bladder base than the urethra. Autonomic efferent innervation to the upper two thirds of the vagina is through the utervaginal plexus, which contains both sympathetic and parasympathetic fibers. The body of the clitoris consists of two paired erectile chambers composed of endothelial-lined lacunar spaces, trabecular smooth muscle and trabecular connective tissue collagen and elastin surrounded by a fibrous sheath, the tunica albuginea.
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